Abnormalities in the hippocampus are associated with neuropsychiatric diseases characterized by cognitive dysfunction...

Maintenance of Neuronal positioning for Learning & Memory

Epilepsy is a chronic condition whose hallmark feature is the occurrence of spontaneous recurrent seizures, and is typically associated with comorbid conditions, including learning and memory deficits, anxiety and depression...

The Cytoskeleton in Epilepsy:

Cause, Consequence or Bystander?

Amyotrophic lateral sclerosis (ALS) is the most common form of human motor neuron disease...

Pathogenic Mechanisms in Amyotrophic Lateral Sclerosis

The microtubule-associated protein TPX2 is well known for its roles in promoting spindle assembly and regulating mitosis...

From Mitotic Spindle to DNA Damage Response

There is currently no treatment for Alzheimer disease (AD), the most common form of senile dementia affecting ~47 million people worldwide...

Genetic Predisposition Factors in Alzheimer Disease

Protein 600 is a humongous 600 kDa polypeptide...

p600 Links Microtubules to the Endoplasmic Reticulum