The Nguyen laboratory has studied the roles of the cytoskeleton in multiple basic cellular processes including cellular proliferation/differentiation, cell repair, neurogenesis, neuronal migration/positioning, as well as neuronal maintenance and survival. The works are thematically distinct, but they always underscore the long-standing interest of the laboratory to decipher mechanisms that regulate cellular functions and behaviors (see Selected Publications). Because these fundamental cellular processes are deregulated in human diseases, the Nguyen laboratory has undertaken research in the fields of cancer, neurodevelopmental and neurodegenerative disorders.

 

To investigate the cytoskeleton in health and disease, we use a multidisciplinary approach that combines microscopy, molecular biology, biochemistry, primary cell cultures, animal models and imaging techniques.